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  • A new drug approved for weight-loss with the U.S. Food and Drug Administration had good results in clinical trials, nonetheless it isn't a panacea for weight reduction. It must be employed in combination with a low-calorie diet and physical exercise in order to be effective.

    Using two separate drugs to shed pounds can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you need to err to the side of caution and allow the FDA do its job and demand some study be done so that the public knows the side effects and perils associated with the medications before we take them. Keep in mind that drug companies come in business to generate income and that they would say anything to keep people on their medications.

    Researchers found out that participants taking this drug for the year, dropped a few pounds within four weeks and have kept the extra weight off throughout the 56 weeks from the study. Contrave is often a combination from the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, which might make them more effective and safer.

    Combo-pilling is the newest fad or even better the newest into the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular is the fact that as of right now there are no long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA.

    Seizures are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug also can raise blood pressure levels and pulse rate, and mustn't be used in those with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure level and heartbeat and must 't be used in patients with uncontrolled high blood pressure level, as well as by a person with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients for the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

    Approving a drug with this many potentially lethal negative effects is inconsistent with the mission statement from the FDA. The power in the drug manufacturing lobby is blatantly evident inside approval of several drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety within the US.

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